Publications 2018

2018

Tisalgenleucel in adult relapsed or refractory diffuse large B-cell lymphoma.

Schuster SJ, Bishop MR, Tam CS, Waller EK, Borchmann P, McGuirk JP, Jaeger U, Jaglowski S, Andreadis C, Westin JR, Fleury I, Bachanova V, Foley SR, Ho PJ, Mielke S, Magenau JM, Holte H, Pantano S, Pacaud LB, Awasthi R, Chu J, Tai F, Anak O, Salles G, Maziarz RT (2018)

New Engl J Med Dec 1, DOI:10.1056/NEJMoa1804980

2018

Gene therapy in patients with transfusion-dependent beta-thalassemia

Thompson AA,  Walters MC, Kwiatkowski J, Rasko, JEJ, Ribeil, J-A, Hongeng S, Magrin E, Schiller GJ, Payen E, Semeraro M, Moshous D, Lefrere F, Puy H, Bourget P, Magnani A, Caccavelli L, Diana, J-S, Monpoux F, Brousse V, Poirot C, Brouzes C, Meritet J-F, Pondarré C, Beuzard Y, Chrétien S, Lefebvre T, Teachey, DT, Anurathapan U, Ho PJ, von Kalle C, Kletzel M, Vichinsky E, Soni S, Veres G, Negre O, Ross R, Davidson D, Petrusich A, Sandler L, Asmal M, Hermine O, De Montalembert M, Hacein-Bey-Abina S, Blanche S, Leboulch P, Cavazzana M (2018).

New Eng J Med 378:1479-93.

2018

Bone marrow transplantation generates T cell-dependent control of myeloma in mice.

*Vuckovic S, *Minnie SA, Smith D, Gartlan KH, Watkins TS, Markey KA, Mukhopadhyay P, Guillerey C, Kuns RD, Locke KR, Pritchard AL, Johansson PA, Varelias A, Zhang P, Huntington ND, Waddell N, Chesi M, Miles JJ, Smyth MJ, Hill GR. J Clin Invest. J

2018 Oct 9. pii: 98888. doi: 10.1172/JCI98888. [Epub ahead of print] (* these authors contributed equally).

Comment “Autologous graft versus myeloma: it’s not a myth” , published on line November 19, 2018

2018

Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade.

Minnie SA, Kuns RD, Gartlan KH, Zhang P, Wilkinson AN, Samson L, Guillerey C, Engwerda C, MacDonald KPA, Smyth MJ, Markey KA, *Vuckovic S, *Hill GR.

Blood. 2018 Oct 18;132(16):1675-1688. doi: 10.1182/blood-2018-01-825240. Epub 2018 Aug 28. (* these authors contributed equally).

Comment “TIGIT checkpoint inhibition for myeloma”, page 1675.

2018

Granulocytes Are Unresponsive to IL-6 Due to an Absence of gp130.

Wilkinson AN, Gartlan KH, Kelly G, Samson LD, Olver SD, Avery J, Zomerdijk N, Tey SK, Lee JS, *Vuckovic S, *Hill GR.

J Immunol. 2018 May 15;200(10):3547-3555. doi: 10.4049/jimmunol.1701191. Epub 2018 Apr 6. (* these authors contributed equally).

Comment: In this issue: Role of IL-6 in Granulocytes.