Mutation burden in patients with haematological malignancies
The Molecular Haematology Laboratory provides a comprehensive diagnostic service for the detection and quantitation of gene mutations in patients with haematological malignancies.
Molecular assays for complex gene rearrangements are performed using techniques such as digital PCR which are capable of achieving single molecule level of sensitivity.
This enables the clinician to more dynamically monitor a patient’s response to therapy.
The laboratory is constantly adapting to new technology and the range of tests is expanded as knowledge about the pathogenesis of leukaemias and myeloproliferative disorders increases.
The recent acquisition of MiSEQ next generation sequencing technology will greatly enhance our molecular diagnostic and research capacity.
